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Magic™ Membrane Protein Human LBR (Lamin B receptor) Full Length (CAT#: MPC2871K) Made to Order

This product is a made-to-order Human LBR membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LBR
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 8
  • Sequence
  • MPSRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELK
    ENDIKPLTSFRQRKGGSTSSSPSRRRGSRSRSRSRSPGRPPKSARRSASA
    SHQADIKEARREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQ
    EKFSLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAKELAVRTFEVT
    PIRAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCKQKDPSLLNFPPPLPAL
    YELWETRVFGVYLLWFLIQVLFYLLPIGKVVEGTPLIDGRRLKYRLNGFY
    AFILTSAVIGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLK
    APRNDLSPASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVIN
    LVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVDALWNEEALLTTMDIIHD
    GFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMASLIIVLKLCGYVI
    FRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLG
    DLIMALAWSLPCGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWE
    KYCQRVPYRIFPYIY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • LBR
  • Full Name
  • Lamin B receptor
  • Introduction
  • The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
  • Alternative Names
  • LBR; PHA; C14SR; LMN2R; PHASK; TDRD18; DHCR14B; delta(14)-sterol reductase LBR; 3-beta-hydroxysterol Delta (14)-reductase; C-14 sterol reductase; delta-14-SR; integral nuclear envelope inner membrane protein; sterol C14-reductase; tudor domain containing 18; Lamin B receptor

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