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Magic™ Membrane Protein Human LILRA5 (Leukocyte immunoglobulin like receptor A5) Expressed in CHO for Antibody Discovery, Partial (42-268aa) (CAT#: MPX0620K)

Datasheet
This product is a 26 kDa Human LILRA5 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LILRA5
  • Protein Length
  • Partial (42-268aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 26 kDa
  • TMD
  • 1
  • Sequence
  • GNLSKATLW
    AEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKAR
    FSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSP
    VVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFP
    VGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKS
    DSGTASHLQDYAVENLIR

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • LILRA5
  • Full Name
  • Leukocyte immunoglobulin like receptor A5
  • Introduction
  • The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described.
  • Alternative Names
  • LILRA5; CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7; leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; immunoglobulin-like transcript 11 protein; leucocyte Ig-like receptor A5; leukocyte Ig-like receptor 9; leukocyte immunoglobulin-like receptor 9; leukocyte immunoglobulin-like receptor subfamily A member 5 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7; Leukocyte immunoglobulin like receptor A5

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