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Magic™ Membrane Protein Human LRP8 (LDL receptor related protein 8) Full Length (CAT#: MPC1625K) Made to Order

This product is a 105.6 kDa Human LRP8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LRP8
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 105.6 kDa
  • TMD
  • 1
  • Sequence
  • MGLPEPGPLRLLALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKD
    QFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIH
    ERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDG
    EKDCEGGADEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERG
    CADPACGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAAELCGRPGP
    GATSAPAACATASQFACRSGECVHLGWRCDGDRDCKDKSDEADCPLGTCR
    GDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGCSHI
    CTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCE
    CYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLK
    NVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPE
    GLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPL
    RGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYW
    VDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEA
    IFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGC
    EYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASTM
    TRTVPATTRAPGTTVHRSTYQNHSTETPSLTAAVPSSVSVPRAPSISPST
    LSPATSNHSQHYANEDSKMGSTVTAAVIGIIVPIVVIALLCMSGYLIWRN
    WKRKNTKSMNFDNPVYRKTTEEEDEDELHIGRTAQIGHVYPAAISSFDRP
    LWAEPCLGETREPEDPAPALKELFVLPGEPRSQLHQLPKNPLSELPVVKS
    KRVALSLEDDGLP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • LRP8
  • Full Name
  • LDL receptor related protein 8
  • Introduction
  • This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • LRP8; MCI1; LRP-8; APOER2; HSZ75190; low-density lipoprotein receptor-related protein 8; ApoE receptor 2; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; LDL receptor related protein 8

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