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Magic™ Membrane Protein Human MCOLN2 (Mucolipin TRP cation channel 2) Full Length (CAT#: MPC0663K) Made to Order

This product is a 65.9 kDa Human MCOLN2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MCOLN2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 65.9 kDa
  • TMD
  • 6
  • Sequence
  • MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFM
    SPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVA
    FKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLG
    YGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSK
    KPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQNTI
    IFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVI
    CLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLV
    IISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYF
    QAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLN
    TVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILS
    LFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSCI
    CCRRRKRSDDHLIPIS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • MCOLN2
  • Full Name
  • Mucolipin TRP cation channel 2
  • Introduction
  • Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV.
  • Alternative Names
  • TRPML2; TRP-ML2; mucolipin-2; mucolipin 2; transient receptor potential channel mucolipin 2; MCOLN2; Mucolipin TRP cation channel 2

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