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Magic™ Membrane Protein Human MR1 (Major histocompatibility complex, class I-related) Full Length (CAT#: MPC4191K) Made to Order

This product is a made-to-order Human MR1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MR1
  • Protein Length
  • Full length
  • Protein Class
  • Immunity
  • TMD
  • 1
  • Sequence
  • MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYV
    DSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELK
    RLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLS
    WLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQR
    TEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYG
    DILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
    VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • MR1
  • Full Name
  • Major histocompatibility complex, class I-related
  • Introduction
  • MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
  • Alternative Names
  • MR1; HLALS; MHC class I-like antigen MR-1; MHC class-I related-gene protein; major histocompatibility complex, class I-like sequence; major histocompatibility complex class I-related gene protein; Major histocompatibility complex, class I-related

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