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Magic™ Membrane Protein Human MTNR1A (Melatonin receptor 1A) Full Length (CAT#: MPC0297K) Made to Order

Datasheet
This product is a 39.3 kDa Human MTNR1A membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MTNR1A
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 39.3 kDa
  • TMD
  • 7
  • Sequence
  • MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVIL
    SVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHC
    QVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLL
    IWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPM
    IIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAIC
    WAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
    NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag and 10xHis tag at N-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • MTNR1A
  • Full Name
  • Melatonin receptor 1A
  • Introduction
  • This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
  • Alternative Names
  • MT1; MEL-1A-R; melatonin receptor type 1A; mel1a receptor; MTNR1A; Melatonin receptor 1A

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