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Magic™ Membrane Protein Human MUC16 (Mucin 16, cell surface associated) Full Length (CAT#: MPC1918K) Made to Order

This product is a 1519.1 kDa Human MUC16 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MUC16
  • Protein Length
  • Full length or ECD
  • Protein Class
  • Transporter
  • Molecular Weight
  • 1519.1 kDa
  • TMD
  • 1
  • Sequence
  • MLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVV
    TEHTLPFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQR
    TSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEASTYTLT
    VETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADST
    ASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRG
    ETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSI
    FSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSL
    GTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTS
    TSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESE
    MTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAH
    GSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPA
    STSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTT
    HQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVS
    VSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTP
    LNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATS
    SITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGE
    ETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTF
    SSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPT
    MDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQ
    TNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSK
    FTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEG
    RLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTS
    QFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTW
    LGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTS
    LTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPS
    IHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYS
    SGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTT
    ENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTK
    LAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQ
    TTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS
    KSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEH
    STQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSS
    SEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHL
    PIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRV
    SSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIP
    LTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTAL
    GSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHG
    VHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTE
    KSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTG
    ITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQ
    STPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITS
    WLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSA
    AKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAI
    TSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDP
    WTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTV
    SFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAM
    STKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVK
    TSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMT
    ASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTL
    PPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVP
    APGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAV
    VTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVVT
    ETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAI
    PLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLK
    TVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALST
    LPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGG
    IRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPV
    KPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSL
    DTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISA
    SSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKA
    SSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTS
    RKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTI
    AEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISV
    PAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSP
    EMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQST
    ALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGT
    PGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGS
    TGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIP
    STVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTL
    YITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRA
    NVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSI
    STTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSN
    LKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDAS
    AVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSST
    EAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATAT
    TSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTF
    SRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATF
    QRQGQTALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSS
    SSVLRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNT
    VETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWP
    ESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTE
    ITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPP
    GATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSP
    PSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGL
    GKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVT
    NMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIE
    TVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSG
    TSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQTGPTGAATQG
    PYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTSPPSVAET
    SYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTS
    MEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHV
    LHSTLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLT
    AGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPA
    QSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTST
    LETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAP
    VLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSS
    PQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSA
    YPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRET
    SISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSL
    DISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQA
    GIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMT
    TPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSST
    SDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKA
    TTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQE
    SSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTG
    EIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHST
    VTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPV
    SSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITH
    ERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKAT
    PLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSS
    TTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRPTIAPDISTGMITR
    LFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQG
    FPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSP
    ESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTT
    YKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMG
    ITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETS
    TVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTF
    PFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHS
    EETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSS
    PTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEAST
    NTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMED
    AIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSV
    SLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTIS
    THKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVM
    NNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVS
    VTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSIN
    TAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRS
    SAMKKIESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSR
    TELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTG
    PHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGT
    SPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLV
    KTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTT
    TSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEME
    STFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTS
    IPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGT
    FTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTS
    FSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSP
    EPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGS
    QSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLT
    PGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPS
    QSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTS
    TTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLL
    SLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTS
    SPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSAL
    ADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRE
    TGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTML
    PEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPS
    LVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSA
    MISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPS
    LSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSE
    TTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTS
    EETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDIS
    IGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETH
    SIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPH
    PVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTS
    HERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTT
    STMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMST
    VLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTES
    AEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLM
    RRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLP
    VTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDTEKT
    HPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVST
    STPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGAT
    AEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMI

    KTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPG
    DMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVTSLL
    NPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTH
    TAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDF
    FETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSR
    TEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETG
    SPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWP
    SLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVK
    TTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNV
    GTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMT
    QPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGR
    TSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQG
    TFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKT
    SPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDT
    SLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQ
    EFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTL
    TPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQ
    STMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTST
    TFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSS
    PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSP
    PNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKA
    TSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETS
    SATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETI
    TRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATT
    QRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYS
    TPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITSDESL
    AASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVV
    TSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTET
    STVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLST
    SPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHS
    EMTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSS
    PSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIM
    TDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAVD
    DTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYG
    VPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSE
    STQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLM
    SRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSV
    TSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSS
    SMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPA
    NFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSK
    TDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESR
    FTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISG
    SGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHE
    ITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTR
    MTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVK
    GPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATLTTSVYT
    PTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETS
    TALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWV
    IHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELD
    ALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPN
    FSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNM
    TIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSL
    AAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTT
    PSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSP
    GEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIP
    ILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTS
    TTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSS
    GVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTP
    LVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPG
    MVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAV
    SPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVV
    PTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPE
    AESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASW
    VTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDV
    PDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTL
    PVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNT
    MVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLV
    PSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGS
    DTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLT
    PSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTP
    VSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSS
    GAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTA
    SLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPL
    STHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVS
    GLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEM
    PTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGS
    LFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVT
    STFSPGISTSSIPSSTAATVPFMVPFTLNFTITNLQYEEDMRHPGSRKFN
    ATERELQGLLKPLFRNSSLEYLYSGCRLASLRPEKDSSATAVDAICTHRP
    DPEDLGLDRERLYWELSNLTNGIQELGPYTLDRNSLYVNGFTHRSSMPTT
    STPGTSTVDVGTSGTPSSSPSPTTAGPLLMPFTLNFTITNLQYEEDMRRT
    GSRKFNTMESVLQGLLKPLFKNTSVGPLYSGCRLTLLRPEKDGAATGVDA
    ICTHRLDPKSPGLNREQLYWELSKLTNDIEELGPYTLDRNSLYVNGFTHQ
    SSVSTTSTPGTSTVDLRTSGTPSSLSSPTIMAAGPLLVPFTLNFTITNLQ
    YGEDMGHPGSRKFNTTERVLQGLLGPIFKNTSVGPLYSGCRLTSLRSEKD
    GAATGVDAICIHHLDPKSPGLNRERLYWELSQLTNGIKELGPYTLDRNSL
    YVNGFTHRTSVPTSSTPGTSTVDLGTSGTPFSLPSPATAGPLLVLFTLNF
    TITNLKYEEDMHRPGSRKFNTTERVLQTLLGPMFKNTSVGLLYSGCRLTL
    LRSEKDGAATGVDAICTHRLDPKSPGVDREQLYWELSQLTNGIKELGPYT
    LDRNSLYVNGFTHWIPVPTSSTPGTSTVDLGSGTPSSLPSPTTAGPLLVP
    FTLNFTITNLKYEEDMHCPGSRKFNTTERVLQSLLGPMFKNTSVGPLYSG
    CRLTLLRSEKDGAATGVDAICTHRLDPKSPGVDREQLYWELSQLTNGIKE
    LGPYTLDRNSLYVNGFTHQTSAPNTSTPGTSTVDLGTSGTPSSLPSPTSA
    GPLLVPFTLNFTITNLQYEEDMHHPGSRKFNTTERVLQGLLGPMFKNTSV
    GLLYSGCRLTLLRPEKNGAATGMDAICSHRLDPKSPGLNREQLYWELSQL
    THGIKELGPYTLDRNSLYVNGFTHRSSVAPTSTPGTSTVDLGTSGTPSSL
    PSPTTAVPLLVPFTLNFTITNLQYGEDMRHPGSRKFNTTERVLQGLLGPL
    FKNSSVGPLYSGCRLISLRSEKDGAATGVDAICTHHLNPQSPGLDREQLY
    WQLSQMTNGIKELGPYTLDRNSLYVNGFTHRSSGLTTSTPWTSTVDLGTS
    GTPSPVPSPTTTGPLLVPFTLNFTITNLQYEENMGHPGSRKFNITESVLQ
    GLLKPLFKSTSVGPLYSGCRLTLLRPEKDGVATRVDAICTHRPDPKIPGL
    DRQQLYWELSQLTHSITELGPYTLDRDSLYVNGFTQRSSVPTTSTPGTFT
    VQPETSETPSSLPGPTATGPVLLPFTLNFTITNLQYEEDMRRPGSRKFNT
    TERVLQGLLMPLFKNTSVSSLYSGCRLTLLRPEKDGAATRVDAVCTHRPD
    PKSPGLDRERLYWKLSQLTHGITELGPYTLDRHSLYVNGFTHQSSMTTTR
    TPDTSTMHLATSRTPASLSGPMTASPLLVLFTINFTITNLRYEENMHHPG
    SRKFNTTERVLQGLLRPVFKNTSVGPLYSGCRLTLLRPKKDGAATKVDAI
    CTYRPDPKSPGLDREQLYWELSQLTHSITELGPYTLDRDSLYVNGFTQRS
    SVPTTSIPGTPTVDLGTSGTPVSKPGPSAASPLLVLFTLNFTITNLRYEE
    NMQHPGSRKFNTTERVLQGLLRSLFKSTSVGPLYSGCRLTLLRPEKDGTA
    TGVDAICTHHPDPKSPRLDREQLYWELSQLTHNITELGPYALDNDSLFVN
    GFTHRSSVSTTSTPGTPTVYLGASKTPASIFGPSAASHLLILFTLNFTIT
    NLRYEENMWPGSRKFNTTERVLQGLLRPLFKNTSVGPLYSGCRLTLLRPE
    KDGEATGVDAICTHRPDPTGPGLDREQLYLELSQLTHSITELGPYTLDRD
    SLYVNGFTHRSSVPTTSTGVVSEEPFTLNFTINNLRYMADMGQPGSLKFN
    ITDNVMQHLLSPLFQRSSLGARYTGCRVIALRSVKNGAETRVDLLCTYLQ
    PLSGPGLPIKQVFHELSQQTHGITRLGPYSLDKDSLYLNGYNEPGPDEPP
    TTPKPATTFLPPLSEATTAMGYHLKTLTLNFTISNLQYSPDMGKGSATFN
    STEGVLQHLLRPLFQKSSMGPFYLGCQLISLRPEKDGAATGVDTTCTYHP
    DPVGPGLDIQQLYWELSQLTHGVTQLGFYVLDRDSLFINGYAPQNLSIRG
    EYQINFHIVNWNLSNPDPTSSEYITLLRDIQDKVTTLYKGSQLHDTFRFC
    LVTNLTMDSVLVTVKALFSSNLDPSLVEQVFLDKTLNASFHWLGSTYQLV
    DIHVTEMESSVYQPTSSSSTQHFYLNFTITNLPYSQDKAQPGTTNYQRNK
    RNIEDALNQLFRNSSIKSYFSDCQVSTFRSVPNRHHTGVDSLCNFSPLAR
    RVDRVAIYEEFLRMTRNGTQLQNFTLDRSSVLVDGYSPNRNEPLTGNSDL
    PFWAVILIGLAGLLGVITCLICGVLVTTRRRKKEGEYNVQQQCPGYYQSH
    LDLEDLQ

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • MUC16
  • Full Name
  • Mucin 16, cell surface associated
  • Introduction
  • This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.
  • Alternative Names
  • MUC16; CA125; mucin-16; CA125 ovarian cancer antigen; cancer antigen 125; ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125; Mucin 16, cell surface associated

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