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Magic™ Membrane Protein Human NMBR (Neuromedin B receptor) Full Length (CAT#: MPC0299K) Made to Order

This product is a 43.4 kDa Human NMBR membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NMBR
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 43.4 kDa
  • TMD
  • 7
  • Sequence
  • MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLY
    LLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVD
    ASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMD
    MQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIP
    YPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEY
    NEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSL
    GHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERG
    TSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • NMBR
  • Full Name
  • Neuromedin B receptor
  • Introduction
  • This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants.
  • Alternative Names
  • BB1; BB1R; NMB-R; neuromedin-B receptor; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; epididymis tissue protein Li 185a; neuromedin-B-preferring bombesin receptor; NMBR; Neuromedin B receptor

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