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Magic™ Membrane Protein Human NOX4 (NADPH oxidase 4) Full Length (CAT#: MPC0673K) Made to Order

This product is a 66.9 kDa Human NOX4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NOX4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 66.9 kDa
  • TMD
  • 6
  • Sequence
  • MAVSWRSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQML
    GLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDK
    SRTFHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDED
    PRKLLFTTVPGLTGVCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVF
    YMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEP
    FPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLY
    RYIRSNKPVTIISVMSHPSDVMEIRMVKENFKARPGQYITLHCPSVSALE
    NHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQ
    SRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWK
    PYKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENRPDYVNIQLYLSQ
    TDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPN
    SLSKTLHKLSNQNNSYGTRFEYNKESFS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • NOX4
  • Full Name
  • NADPH oxidase 4
  • Introduction
  • This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • KOX; KOX-1; RENOX; kidney oxidase-1; kidney superoxide-producing NADPH oxidase; renal NAD(P)H-oxidase; NOX4; NADPH oxidase 4

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