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Magic™ Membrane Protein Human NTRK3 (Neurotrophic receptor tyrosine kinase 3) Full Length (CAT#: MPC1446K) Made to Order

This product is a 94.4 kDa Human NTRK3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NTRK3
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 94.4 kDa
  • TMD
  • 1
  • Sequence
  • MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDD
    GNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDME
    LYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTL
    SLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLF
    RMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQS
    INTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALT
    VYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHV
    EYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPF
    PESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLF
    VMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDT
    VVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFG
    KVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI
    VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGE
    LGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGM
    SRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTE
    SDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVY
    DVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • NTRK3
  • Full Name
  • Neurotrophic receptor tyrosine kinase 3
  • Introduction
  • This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • NTRK3; TRKC; GP145-TrkC; gp145(trkC); NT-3 growth factor receptor; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; neurotrophic tyrosine kinase, receptor, type 3; tyrosine kinase receptor C; Neurotrophic receptor tyrosine kinase 3

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