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Magic™ Membrane Protein Human OLR1 (Oxidized low density lipoprotein receptor 1) expressed in E. coli for Antibody Discovery (CAT#: MP0018Q)

Datasheet
This product is a 24.7 kDa Human OLR1 membrane protein expressed in E. col. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • OLR1
  • Protein Length
  • Partial
  • Protein Class
  • Druggable Genome, Secreted Protein, Transmembrane
  • Molecular Weight
  • 24.7 kDa
  • TMD
  • 1
  • Sequence
  • MQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ

Product Description

  • Expression Systems
  • E. coli
  • Purification
  • Conventional chromatography
  • Purity
  • >90%
  • Buffer
  • 20mM Tris-HCl buffer (pH 8.0) containing 5% glycerol, 0.4M Urea

Target

  • Target Protein
  • OLR1
  • Full Name
  • Oxidized low density lipoprotein receptor 1
  • Introduction
  • This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • CLEC8A; LOX1; LOXIN; SCARE1; SLOX1; C-type lectin domain family 8 member A; hLOX-1; Lectin-like oxidized LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1; hLOX-1; Lectin-type oxidized LDL receptor 1; ox LDL receptor 1; Oxidized low-density lipoprotein receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; scavenger receptor class E, member 1

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