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Magic™ Membrane Protein Human ORAI1 (ORAI calcium release-activated calcium modulator 1) Full Length (CAT#: MPC1013K) Made to Order

This product is a 32.6 kDa Human ORAI1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ORAI1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 32.6 kDa
  • TMD
  • 4
  • Sequence
  • MHPEPAPPPSRSSPELPPSGGSTTSGSRRSRRRSGDGEPPGAPPPPPSAV
    TYPDWIGQSYSEVMSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFA
    MVAMVEVQLDADHDYPPGLLIAFSACTTVLVAVHLFALMISTCILPNIEA
    VSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFL
    PLKKQPGQPRPTSKPPASGAAANVSTSGITPGQAAAIASTTIMVPFGLIF
    IVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHPLTPGSHY
    A

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ORAI1
  • Full Name
  • ORAI calcium release-activated calcium modulator 1
  • Introduction
  • The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
  • Alternative Names
  • ORAI1; IMD9; TAM2; ORAT1; CRACM1; TMEM142A; calcium release-activated calcium channel protein 1; calcium release-activated calcium modulator 1; protein orai-1; transmembrane protein 142A; ORAI calcium release-activated calcium modulator 1

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