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Magic™ Membrane Protein Human P2RX6 (Purinergic receptor P2X 6) Full Length (CAT#: MPC0685K) Made to Order

This product is a 48.8 kDa Human P2RX6 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RX6
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 48.8 kDa
  • TMD
  • 2
  • Sequence
  • MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIV
    VYVVGWALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADF
    VKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGG
    THSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFI
    KNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKA
    GGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTAT
    HWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGV
    VTFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLA
    ECLRRSSAPAPTATAAGSQTQTPGWPCPSSDTHLPTHSGSL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • P2RX6
  • Full Name
  • Purinergic receptor P2X 6
  • Introduction
  • The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
  • Alternative Names
  • P2X6; P2XM; P2RXL1; P2X purinoceptor 6; ATP receptor; purinergic receptor P2X, ligand gated ion channel, 6; purinergic receptor P2X-like 1, orphan receptor; purinoceptor P2X6; purinoreceptor P2X6; skeletal muscle-expressed P2X; P2RX6; Purinergic receptor P2X 6

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