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Magic™ Membrane Protein Human P2RY6 (Pyrimidinergic receptor P2Y6) Full Length (CAT#: MPC0221K) Made to Order

This product is a 36.4 kDa Human P2RY6 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RY6
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 36.4 kDa
  • TMD
  • 7
  • Sequence
  • MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQ
    ICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACR
    LVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVA
    VWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIG
    FLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAI
    SFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
    FYFTQKKFRRRPHELLQKLTAKWQRQGR

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • P2RY6
  • Full Name
  • Pyrimidinergic receptor P2Y6
  • Introduction
  • The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
  • Alternative Names
  • P2Y6; P2Y purinoceptor 6; G-coupled nucleotide receptor; P2 purinoceptor; P2Y6 receptor; pyrimidinergic receptor P2Y, G-protein coupled, 6; P2RY6; Pyrimidinergic receptor P2Y6

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