Close
Close

Magic™ Membrane Protein Human PDGFRA (Platelet derived growth factor receptor alpha) Expressed in HEK293 for Antibody Discovery, Partial (24-524aa) (CAT#: MPX0330K)

Datasheet
This product is a 59 kDa Human PDGFRA membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PDGFRA
  • Protein Length
  • Partial (24-524aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 59 kDa
  • TMD
  • 1
  • Sequence
  • QLSLPSILPNENEKVVQLNSSFSLRCF
    GESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTC
    YYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPC
    RTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQT
    IPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYP
    GEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVK
    EMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWL
    KNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNED
    AVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMIC
    KDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVR
    CLAKNLLGAENRELKLVAPTLRSE

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • 6xHis and Avi tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Target

  • Target Protein
  • PDGFRA
  • Full Name
  • Platelet derived growth factor receptor alpha
  • Introduction
  • This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
  • Alternative Names
  • PDGFRA; CD140A; PDGFR2; PDGFR-2; platelet-derived growth factor receptor alpha; CD140 antigen-like family member A; CD140a antigen; PDGF-R-alpha; alpha-type platelet-derived growth factor receptor; platelet-derived growth factor receptor 2; platelet-derived growth factor receptor, alpha polypeptide; Platelet derived growth factor receptor alpha

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us