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Magic™ Membrane Protein Human PORCN (Porcupine O-acyltransferase) Full Length (CAT#: MPC3014K) Made to Order

This product is a made-to-order Human PORCN membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PORCN
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 8
  • Sequence
  • MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSY
    LKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLS
    VTILIYLLMGEMHMVDTVTWHKMRGAQMIVAMKAVSLGFDLDRGEVGTVP
    SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALA
    LLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVS
    FHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
    VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAV
    LLSLAFITYVEHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNL
    LFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVT
    FGCWIFYRLIG

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • PORCN
  • Full Name
  • Porcupine O-acyltransferase
  • Introduction
  • This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
  • Alternative Names
  • PORCN; PPN; DHOF; FODH; MG61; PORC; protein-serine O-palmitoleoyltransferase porcupine; porcupine homolog; probable protein-cysteine N-palmitoyltransferase porcupine; Porcupine O-acyltransferase

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