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Magic™ Membrane Protein Human PPT1 (Palmitoyl-protein thioesterase 1) Expressed in HEK293, Full Length (CAT#: MPX1985K)

This product is a Human PPT1 protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PPT1
  • Protein Length
  • Full Length
  • Protein Class
  • Hydrolase
  • Molecular Weight
  • 58.3 kDa
  • Sequence
  • MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • < 1.0 EU per μg of the protein as determined by the LAL method
  • Purity
  • > 85 % as determined by SDS-PAGE
  • Buffer
  • Lyophilized from sterile PBS, pH 7.4.

Target

  • Target Protein
  • PPT1
  • Full Name
  • Palmitoyl-protein thioesterase 1
  • Introduction
  • The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • PPT; CLN1; INCL; palmitoyl-protein thioesterase 1; ceroid-palmitoyl-palmitoyl-protein thioesterase 1; palmitoyl-protein hydrolase 1

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