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Magic™ Membrane Protein Human PRLR (Prolactin receptor) Expressed in NS0 for Antibody Discovery, Partial (25-234aa) (CAT#: MPX0463K)

Datasheet
This product is a 51 kDa Human PRLR membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PRLR
  • Protein Length
  • Partial (25-234aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 51 kDa
  • TMD
  • 1
  • Sequence
  • QLPPGKPEIFKCRSPNKETFTCWWRP
    GTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYI
    MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIK
    WSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQ
    KYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMND

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • PRLR
  • Full Name
  • Prolactin receptor
  • Introduction
  • This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
  • Alternative Names
  • PRLR; HPRL; MFAB; hPRLrI; RI-PRLR; hPRL receptor; secreted prolactin binding protein; Prolactin receptor

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