Magic™ Membrane Protein Human PTK7 (Protein tyrosine kinase 7 (inactive)) Expressed in HEK293 for Antibody Discovery, Partial (1-704aa) (CAT#: MPX0566K)

Datasheet

This product is a 101 kDa Human PTK7 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
PTK7

Protein Length
Partial (1-704aa)

Protein Class
Cell adhesion

Molecular Weight
101 kDa

Sequence
MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRAL
LRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQ
CVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRC
HIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSC
CAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSA
QPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLP
EPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQR
RQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM
LISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE
KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEWVTD
NAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLV
IHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYK
MIQT

Product Description

Activity
Yes

Expression Systems
HEK293

Tag
hIgG1 Fc tag at the C-terminus

Protein Format
Soluble

Reconstitution
Reconstitute at 500 μg/mL in PBS.

Endotoxin
<0.10 EU per 1 μg of the protein by the LAL method.

Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Buffer
Lyophilized from a 0.2 μm filtered solution in PBS.

Target

Target Protein
PTK7

Full Name
Protein tyrosine kinase 7 (inactive)

Introduction
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative Names
PTK7; CCK4; CCK-4; inactive tyrosine-protein kinase 7; PTK7 protein tyrosine kinase 7; colon carcinoma kinase 4; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7; Protein tyrosine kinase 7 (inactive)

Gene ID
5754

UniProt ID
Q13308

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