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Magic™ Membrane Protein Human RAET1E (Retinoic acid early transcript 1E) Expressed in NS0 for Antibody Discovery, Partial (30-225aa) (CAT#: MPX0434K)

Datasheet
This product is a 49 kDa Human RAET1E membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RAET1E
  • Protein Length
  • Partial (30-225aa)
  • Protein Class
  • Immunity
  • Molecular Weight
  • 49 kDa
  • TMD
  • 1
  • Sequence
  • GHSLCFNFTIKSLSRPGQPWC
    EAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRD
    LRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLF
    DAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHW
    EAMPEPTVSPVNASDIHWSSSSLPD

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in PBS.
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • RAET1E
  • Full Name
  • Retinoic acid early transcript 1E
  • Introduction
  • This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • RAET1E; RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7; NKG2D ligand 4; RAE-1-like transcript 4; UL16-binding protein 4; lymphocyte effector toxicity activation ligand; Retinoic acid early transcript 1E

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