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Magic™ Membrane Protein Human RNF128 (Ring finger protein 128) Full Length (CAT#: MPC2445K) Made to Order

This product is a made-to-order Human RNF128 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RNF128
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 1
  • Sequence
  • MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVS
    WRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHT
    NFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPG
    TRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHG
    PWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKAD
    AKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFH
    KTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSA
    SSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAV
    DVIPHVDNPTFEEDETPNQETAVREIKS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • RNF128
  • Full Name
  • Ring finger protein 128
  • Introduction
  • The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
  • Alternative Names
  • RNF128; GRAIL; E3 ubiquitin-protein ligase RNF128; RING-type E3 ubiquitin transferase RNF128; gene related to anergy in lymphocytes protein; ring finger protein 128, E3 ubiquitin protein ligase; Ring finger protein 128

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