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Magic™ Membrane Protein Human RRBP1 (Ribosome binding protein 1) Full Length (CAT#: MPC4520K) Made to Order

Datasheet
This product is a made-to-order Human RRBP1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RRBP1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 1
  • Sequence
  • MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMA
    KTHHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDPAPNVTVLLREPV
    RAPAVAVAPTPVQPPIIVAPVATVPAMPQEKLASSPKDKKKKEKKVAKVE
    PAVSSVVNSIQVLTSKAAILETAPKEVPMVVVPPVGAKGNTPATGTTQGK
    KAEGTQNQSKKAEGAPNQGRKAEGTPNQGKKTEGTPNQGKKAEGTPNQGK
    KAEGTPNQGKKAEGAQNQGKKVDTTPNQGKKVEGAPTQGRKAEGAQNQAK
    KVEGAQNQGKKAEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGK
    KAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGK
    KAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGK
    KAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGK
    KAEGAQNQGQKGEGAQNQGKKTEGAQGKKAERSPNQGKKGEGAPIQGKKA
    DSVANQGTKVEGITNQGKKAEGSPSEGKKAEGSPNQGKKADAAANQGKKT
    ESASVQGRNTDVAQSPEAPKQEAPAKKKSGSKKKGEPGPPDADGPLYLPY
    KTLVSTVGSMVFNEGEAQRLIEILSEKAGIIQDTWHKATQKGDPVAILKR
    QLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLVA
    REQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQ
    ENSILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQ
    QRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHAS
    LRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAEN
    SQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE
    KEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKE
    ESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHP
    PAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVE
    EEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSH
    LEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDE
    LALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAI
    LEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLK
    ERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAED
    GSSSKEGTSV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • RRBP1
  • Full Name
  • Ribosome binding protein 1
  • Introduction
  • This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
  • Alternative Names
  • RRBP1; RRp; hES; p180; ES130; ES/130; 180 kDa ribosome receptor homolog; ES/130-related protein; endoplasmic reticulum ribosome-binding protein 1; ribosomal receptor-binding protein 1; ribosome binding protein 1 homolog 180kDa (dog); ribosome receptor protein; Ribosome binding protein 1

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