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Magic™ Membrane Protein Human S1PR5 (Sphingosine-1-phosphate receptor 5) Full Length (CAT#: MPC0241K) Made to Order

This product is a 41.7 kDa Human S1PR5 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • S1PR5
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 41.7 kDa
  • TMD
  • 7
  • Sequence
  • MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFI
    VLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLT
    LKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGR
    TLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLA
    FVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALL
    RTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
    LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRR
    CLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • S1PR5
  • Full Name
  • Sphingosine-1-phosphate receptor 5
  • Introduction
  • The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.
  • Alternative Names
  • EDG8; S1P5; Edg-8; SPPR-1; SPPR-2; S1P receptor 5; S1P receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; S1PR5; Sphingosine-1-phosphate receptor 5

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