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Magic™ Membrane Protein Human SCN1B (Sodium voltage-gated channel beta subunit 1) Full Length (CAT#: MPC0700K) Made to Order

This product is a 24.7 kDa Human SCN1B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCN1B
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 24.7 kDa
  • TMD
  • 1
  • Sequence
  • MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETN
    AETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKD
    LQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKA
    NRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEY
    LAITSESKENCTGVQVAE

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SCN1B
  • Full Name
  • Sodium voltage-gated channel beta subunit 1
  • Introduction
  • Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • DEE52; ATFB13; BRGDA5; EIEE52; GEFSP1; sodium channel subunit beta-1; sodium channel, voltage gated, type I beta subunit; sodium channel, voltage-gated, type I, beta; SCN1B; Sodium voltage-gated channel beta subunit 1

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