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Magic™ Membrane Protein Human SCN3B (Sodium voltage-gated channel beta subunit 3) for Antibody Discovery (CAT#: MP1232J)

This product is a 22.1 kDa Human SCN3B membrane protein expressed in HEK293T. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCN3B
  • Protein Length
  • Full-length
  • Protein Class
  • Druggable Genome, Ion Channels: Sodium, Transmembrane
  • Molecular Weight
  • 22.1 kDa
  • TMD
  • 1
  • Sequence
  • MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGK
    DFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRL
    IPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSA
    VPVEE

Product Description

  • Expression Systems
  • HEK293T
  • Tag
  • C-Myc/DDK
  • Purification
  • Anti-DDK affinity column followed by conventional chromatography steps
  • Purity
  • > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Buffer
  • 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Target

  • Target Protein
  • SCN3B
  • Full Name
  • Sodium voltage-gated channel beta subunit 3
  • Introduction
  • Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
  • Alternative Names
  • ATFB16; BRGDA7; HSA243396; SCNB3; voltage-gated sodium channel beta-3 subunit; sodium channel, voltage-gated, type III, beta subunit

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