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Magic™ Membrane Protein Human SLC12A2 (Solute carrier family 12 member 2) Full Length (CAT#: MPC0723K) Made to Order

This product is a 131.4 kDa Human SLC12A2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC12A2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 131.4 kDa
  • TMD
  • 11
  • Sequence
  • MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPAS
    RDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENAGRAAAAAAAA
    AAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASS
    SAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYY
    YDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDEL
    EKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIW
    GVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGG
    GAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSI
    LMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFV
    IGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATG
    ILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATG
    NVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFT
    PLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNE
    PLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAK
    SPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVT
    YKKPDVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNS
    RPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNK
    MKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDV
    DMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDV
    VVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVP
    LNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWK
    DCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKEN
    IIAFEEIIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQI
    RLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLV
    RGNHQSVLTFYS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • MBP tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC12A2
  • Full Name
  • Solute carrier family 12 member 2
  • Introduction
  • The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.
  • Alternative Names
  • BSC; BSC2; KILQS; NKCC1; PPP1R141; solute carrier family 12 member 2; basolateral Na-K-Cl symporter; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; protein phosphatase 1, regulatory subunit 141; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; SLC12A2; Solute carrier family 12 member 2

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