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Magic™ Membrane Protein Human SLC1A2 (Solute carrier family 1 member 2) Full Length (CAT#: MPC0761K) Made to Order

This product is a 62.1 kDa Human SLC1A2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC1A2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 62.1 kDa
  • TMD
  • 8
  • Sequence
  • MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLT
    VFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISS
    LITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK
    KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPP
    PDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFI
    AFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKI
    IAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAG
    IFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDG
    TALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTM
    LLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSE
    LDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDEC
    KVTLAANGKSADCSVEEEPWKREK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC1A2
  • Full Name
  • Solute carrier family 1 member 2
  • Introduction
  • This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.
  • Alternative Names
  • HBGT; DEE41; EAAT2; GLT-1; EIEE41; excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glutamate/aspartate transporter II; sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; SLC1A2; Solute carrier family 1 member 2

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