Magic™ Membrane Protein Human SLC29A1 (Solute carrier family 29 member 1 (Augustine blood group)) expressed in In vitro wheat germ expression system for Antibody Discovery (CAT#: MP1202X)

Datasheet

This product is a 76.6 kDa Human SLC29A1 membrane protein expressed in In vitro wheat germ expression system with proprietary liposome technology. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
SLC29A1

Protein Length
Full-length

Molecular Weight
76.6 kDa

Sequence
MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDAQASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAILLVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQGLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKLEGPGEQETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIFTITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRWLPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPKKVKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV

Product Description

Application
Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein), Antibody Production, Protein Array

Expression Systems
In vitro wheat germ expression system with proprietary liposome technology

Tag
GST-tag at N-terminal

Purification
Glutathione Sepharose 4 Fast Flow

Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0

Target

Target Protein
SLC29A1

Full Name
Solute carrier family 29 member 1 (Augustine blood group)

Introduction
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Alternative Names
ENT1; equilibrative nucleoside transporter 1; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter; nucleoside transporter, es-type; solute carrier family 29 (equilibrative nucleoside transporter), member 1; solute carrier family 29 (nucleoside transporters), member 1

Gene ID
2030

UniProt ID
Q99808

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