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Magic™ Membrane Protein Human SLC4A8 (Solute carrier family 4 member 8) Full Length (CAT#: MPC0871K) Made to Order

This product is a 122.9 kDa Human SLC4A8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC4A8
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 122.9 kDa
  • TMD
  • 11
  • Sequence
  • MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYV
    GVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQ
    FILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGG
    ERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQEL
    SSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHL
    MDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA
    SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG
    QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGE
    WDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGR
    LFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLL
    GEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFK
    FCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL
    ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQ
    YWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCI
    LFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGV
    PSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMD
    QQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLS
    ITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK
    FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLR
    KVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRE
    LSWLDDLMPESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLESRKLLSS
    PGKNISCRCDPSEINISDEMPKTTVWKALSMNSGNAKEKSLFN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC4A8
  • Full Name
  • Solute carrier family 4 member 8
  • Introduction
  • The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • NBC3; NDCBE; electroneutral sodium bicarbonate exchanger 1; electroneutral Na(+)-driven Cl-HCO3 exchanger; k-NBC3; solute carrier family 4, sodium bicarbonate cotransporter, member 8; SLC4A8; Solute carrier family 4 member 8

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