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Magic™ Membrane Protein Human SLC6A2 (Solute carrier family 6 member 2) Full Length (CAT#: MPC0893K) Made to Order

This product is a 69.3 kDa Human SLC6A2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC6A2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 69.3 kDa
  • TMD
  • 12
  • Sequence
  • MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRD
    GDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTL
    FLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGF
    YYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHT
    KYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYF
    SLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFY
    RLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSIN
    CITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSG
    STFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTFGVT
    FSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDR
    FSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIF
    PPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHL
    VAQRDIRQFQLQHWLAI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC6A2
  • Full Name
  • Solute carrier family 6 member 2
  • Introduction
  • This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
  • Alternative Names
  • NET; NAT1; NET1; SLC6A5; sodium-dependent noradrenaline transporter; neurotransmitter transporter; norepinephrine transporter; solute carrier family 6 (neurotransmitter transporter), member 2; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; solute carrier family 6 member 5; SLC6A2; Solute carrier family 6 member 2

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