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Magic™ Membrane Protein Human SLCO1B1 (Solute carrier organic anion transporter family member 1B1) Full Length (CAT#: MPC0930K) Made to Order

This product is a 76.4 kDa Human SLCO1B1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLCO1B1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 76.4 kDa
  • TMD
  • 12
  • Sequence
  • MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKS
    SIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIG
    CFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQILSL
    NRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFA
    KEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPT
    DSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE
    TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVS
    SYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKF
    KLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTS
    HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIV
    FYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSAL
    GGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI
    KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKK
    YQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETHC

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLCO1B1
  • Full Name
  • Solute carrier organic anion transporter family member 1B1
  • Introduction
  • This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
  • Alternative Names
  • LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6; solute carrier organic anion transporter family member 1B1; OATP-2; liver-specific organic anion transporter 1; sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; SLCO1B1; Solute carrier organic anion transporter family member 1B1

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