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Magic™ Membrane Protein Human SMPD4 (Sphingomyelin phosphodiesterase 4) Full Length (CAT#: MPC4328K) Made to Order

This product is a made-to-order Human SMPD4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SMPD4
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSF
    LLASLKADSINKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDG
    VLVGWNLRCLQGRVNPVEYSIVMEFLDPGGPMMKLVYKLQAEDYKFDFPV
    SYLPGPVKASIQECILPDSPLYHNKVQFTPTGGLGLNLALNPFEYYIFFF
    ALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGSVPPPLSSSPG
    GTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET
    LLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQ
    ALHAYQESFTPTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPL
    EEFKRAAVPRFVQQKLYLFLQHCFGHWPLDASFRAVLEMWLSYLQPWRYA
    PDKQAPGSDSQPRCVSEKWAPFVQENLLMYTKLFVGFLNRALRTDLVSPK
    HALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQHRLFTAPTFTG
    SFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI
    TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDS
    VRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIV
    GEDGLILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASLVRTLFRL
    SSAINHRFAGQMAALCSRDDFLGSFCRYHLTEPGLASRHLLSPVGRRQVA
    GHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCTLLLTLGYVLY
    ASAMTLLTERGKLHQP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SMPD4
  • Full Name
  • Sphingomyelin phosphodiesterase 4
  • Introduction
  • The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.
  • Alternative Names
  • SMPD4; SKNY; NET13; NEDMABA; NEDMEBA; NSMASE3; NSMASE-3; neutral sphingomyelinase 3; neutral sphingomyelinase III; sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3); Sphingomyelin phosphodiesterase 4

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