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Magic™ Membrane Protein Human SPINT2 (Serine peptidase inhibitor, Kunitz type 2) Expressed in NS0 for Antibody Discovery, Partial (1-197aa) (CAT#: MPX0402K)

Datasheet
This product is a 21 kDa Human SPINT2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SPINT2
  • Protein Length
  • Partial (1-197aa)
  • Protein Class
  • Protease inhibitor
  • Molecular Weight
  • 21 kDa
  • TMD
  • 1
  • Sequence
  • MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRAS
    MPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLA
    TSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY
    FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSK

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile, deionized water.
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and CaCl2.

Target

  • Target Protein
  • SPINT2
  • Full Name
  • Serine peptidase inhibitor, Kunitz type 2
  • Introduction
  • This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • SPINT2; PB; Kop; HAI2; DIAR3; HAI-2; kunitz-type protease inhibitor 2; hepatocyte growth factor activator inhibitor type 2; serine protease inhibitor, Kunitz type, 2; testicular tissue protein Li 183; Serine peptidase inhibitor, Kunitz type 2

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