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Magic™ Membrane Protein Human ST6GALNAC1 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1) Expressed in HEK293 for Antibody Discovery, Partial (36-600aa) (CAT#: MPX0668K)

This product is a 65 kDa Human ST6GALNAC1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ST6GALNAC1
  • Protein Length
  • Partial (36-600aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 65 kDa
  • TMD
  • 1
  • Sequence
  • KEPQTKPSRHQRTEN
    IKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDR
    GKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGR
    TEAQSWKSQDTKTTQGNGGQTRKLTASRTVSEKHQGKAATTAKTLIPKSQ
    HRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPFQSPTTQRNQR
    LKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPN
    LTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQL
    LLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGY
    EQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRD
    YEWLEALLMNQTVMSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMK
    NRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFS
    DHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • ST6GALNAC1
  • Full Name
  • ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
  • Introduction
  • Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins.
  • Alternative Names
  • ST6GALNAC1; STYI; SIAT7A; HSY11339; ST6GalNAcI; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; GalNAc alpha-2, 6-sialyltransferase I, long form; SIAT7-A; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6 GalNAc alpha-2,6-sialyltransferase 1; ST6GALNAC1, alpha-2,6-sialyltransferase 1; ST6GalNAc I; galNAc alpha-2,6-sialyltransferase I; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) A; sialyltransferase 7A; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

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