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Magic™ Membrane Protein Human SYNE1 (Spectrin repeat containing nuclear envelope protein 1) Full Length (CAT#: MPC2590K) Made to Order

This product is a made-to-order Human SYNE1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SYNE1
  • Protein Length
  • Full length or ECD
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVV
    DDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLE
    GRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSS
    SASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEV
    KDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETEL
    GIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILP
    GFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQS
    FKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWH
    IQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHK
    DLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHL
    MKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENS
    KFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVE
    VRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNL
    PHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQY
    AQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLE
    DIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVK
    ECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSAL
    FKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQ
    IADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGL
    EEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEA
    VRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMP
    QEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGT
    CHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGI
    KGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEA
    QKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELIS
    GSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQ
    QGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKE
    TVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLV
    KEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDH
    FGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSI
    VGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGH
    LSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQ
    ALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTAL
    ENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQ
    ALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLP
    QIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQ
    VALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCF
    QLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKN
    ESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRA
    TADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEER
    TDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDV
    AFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSK
    VLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGK
    HLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWD
    DVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALR
    LEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLK
    DFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQ
    SQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQ
    ASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQ
    NILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFL
    KQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHI
    PEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQ
    LLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACA
    ESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQ
    RVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWME
    SVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSREL
    YEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVH
    EFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRV
    ESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQ
    MALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWH
    KGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCL
    CLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEV
    STSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAA
    KEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESS
    NRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSF
    RHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAI
    HMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQN
    TSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQ
    FSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIE
    VKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRD
    LKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLN
    SVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKL
    RLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTA
    YRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFL
    EEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTL
    EVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKEL
    TSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELY
    EKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQ
    SDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDL
    LETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQA
    KLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQA
    WLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLS
    NASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDAD
    QQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLT
    KKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVE
    VFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQ
    KMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQ
    SRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQML
    LKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNK
    ALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQ
    ASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKC
    SHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHT
    QLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPR
    QFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKV
    PTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPD
    KMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEE
    QSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLA
    YEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWL
    RRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKE
    KFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQ
    VFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFHSNLE
    ELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCT
    AQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVS
    VVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQ
    DQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTL
    LEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEITAM
    QDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPT
    IEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGLYTILPSELSLQL
    AEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKA
    KTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKK
    IGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLA
    HGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTE
    KMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQ
    AQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPE
    DVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHL
    QQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNS
    KCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTA
    GRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQ
    ALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNV
    ISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQM
    AEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVL
    AERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLL
    STKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENL
    LLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEES
    DVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRS
    VASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWE
    SLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSA
    VTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEER
    LFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDN
    RDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSL
    ADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKL
    QVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLAD
    LLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRK
    IISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQE
    LSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVL
    DDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRY
    QSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVD
    AQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQE
    KLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYL
    QKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMN
    KSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHR
    IGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIV
    MSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEAR
    YSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKE
    CHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQ
    CASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSL
    FFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAG
    VLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQM
    LKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSK
    LQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELF
    QAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRR
    AQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQA
    RTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEI
    QEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSL
    PDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISIL
    NERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQME
    SKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHES
    KASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTW
    LAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLC
    EVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRL
    WQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVH
    ECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSIL
    RRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLK
    AFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVF
    GRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLS
    PQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMS
    RALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQ
    QTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEES
    LPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLN
    SIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIIL
    SINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALM
    QCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKH
    ELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVS
    RHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPR
    GKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALP
    LQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SYNE1
  • Full Name
  • Spectrin repeat containing nuclear envelope protein 1
  • Introduction
  • This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Alternative Names
  • SYNE1; 8B; AMC3; AMCM; CPG2; ARCA1; EDMD4; KASH1; MYNE1; Nesp1; SCAR8; C6orf98; dJ45H2.2; nesprin-1; CPG2 full length; KASH domain-containing protein 1; enaptin; myocyte nuclear envelope protein 1; nesprin 1; spectrin repeat containing, nuclear envelope 1; synaptic nuclear envelope protein 1; synaptic nuclei expressed gene 1; Spectrin repeat containing nuclear envelope protein 1

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