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Magic™ Membrane Protein Human SYNE2 (Spectrin repeat containing nuclear envelope protein 2) Full Length (CAT#: MPC1981K) Made to Order

This product is a 796.4 kDa Human SYNE2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SYNE2
  • Protein Length
  • Full length or ECD
  • Protein Class
  • Receptor
  • Molecular Weight
  • 796.4 kDa
  • TMD
  • 1
  • Sequence
  • MASSPELPTEDEQGSWGIDDLHISLQAEQEDTQKKAFTCWINSQLARHTS
    PSVISDLFTDIKKGHVLLDLLEVLSGQQLPRDKGSNTFQCRINIEHALTF
    LRNRSIKLINIHVTDIIDGNPSIILGLIWTIILHFHIEKLAQTLSCNYNQ
    PSLDDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYES
    VNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAE
    QELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQYSKDAPGTGEEAQGKVK
    DAMGWLTLQKEKLQKLLKDSENDTYFKKYNSLLSFMESFNEEKKSFLDVL
    SIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYALPPPLHQTEAWLQ
    EVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENK
    DENHLPLVPPNKLEEMKRRINNILEKKFILLLEFHYYKCLVLGLVDEVKS
    KLDIWNIKYGSRESVELLLEDWHKFIEEKEFLARLDTSFQKCGEIYKNLA
    GECQNINKQYMMVKSDVCMYRKNIYNVKSTLQKVLACWATYVENLRLLRA
    CFEETKKEEIKEVPFETLAQWNLEHATLNEAGNFLVEVSNDVVGSSISKE
    LRRLNKRWRKLVSKTQLEMNLPLMIKKQDQPTFDNSGNILSKEEKATVEF
    STDMSVELPENYNQNIKAGEKHEKENEEFTGQLKVAKDVEKLIGQVEIWE
    AEAKSVLDQDDVDTSMEESLKHLIAKGSMFDELMARSEDMLQMDIQNISS
    QESFQHVLTTGLQAKIQEAKEKVQINVVKLIAALKNLTDVSPDLDIRLKM
    EESQKELESYMMRAQQLLGQRESPGELISKHKEALIISNTKSLAKYLKAV
    EELKNNVTEDIKMSLEEKSRDVCAKWESLHHELSLYVQQLKIDIEKGKLS
    DNILKLEKQINKEKKLIRRGRTKGLIKEHEACFSEEGCLYQLNHHMEVLR
    ELCEELPSQKSQQEVKRLLKDYEQKIERLLKCASEIHMTLQPTAGGTSKN
    EGTITTSENRGGDPHSEAPFAKSDNQPSTEKAMEPTMKFSLASVLRPLQE
    ESIMEKDYSASINSLLERYDTYRDILEHHLQNNKFRITSDFSSEEDRSSS
    CLQAKLTDLQVIKNETDARWKEFEIISLKLENHVNDIKKPFVIKERDTLK
    ERERELQMTLNTRMESLETALRLVLPVEKASLLLCGSDLPLHKMAIQGFH
    LIDADRIYQHLRNIQDSIAKQIEICNRLEEPGNFVLKELHPFDLHAMQNI
    ILKYKTQFEGMNHRVQRSEDTLKALEDFLASLRTAKLSAEPVTDLSASDT
    QVAQENTLTVKNKEGEIHLMKDKAKHLDKCLKMLDMSFKDAERGDDTSCE
    NLLDAFSIKLSETHGYGVQEEFTEENKLLEACIFKNNELLKNIQDVQSQI
    SKIGLKDPTVPAVKHRKKSLIRLDKVLDEYEEEKRHLQEMANSLPHFKDG
    REKTVNQQCQNTVVLWENTKALVTECLEQCGRVLELLKQYQNFKSILTTL
    IQKEESVISLQASYMGKENLKKRIAEIEIVKEEFNEHLEVVDKINQVCKN
    LQFYLNKMKTFEEPPFEKEANIIVDRWLDINEKTEDYYENLGRALALWDK
    LFNLKNVIDEWTEKALQKMELHQLTEEDRERLKEELQVHEQKTSEFSRRV
    AEIQFLLQSSEIPLELQVMESSILNKMEHVQKCLTGESNCHALSGSTAEL
    REDLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQKHSMILL
    ENQIGCLTPELSELKKQYESVSDLFNTKKSVLQDHFSKLLNDQCKNFNDW
    FSNIKVNLKECFESSETKKSVEQKLQKLSDFLTLEGRNSKIKQVDSVLKH
    VKKHLPKAHVKELISWLVGQEFELEKMESICQARAKELEDSLQQLLRLQD
    DHRNLRKWLTNQEEKWKGMEEPGEKTELFCQALARKREQFESVAQLNNSL
    KEYGFTEEEEIIMEATCLMDRYQTLLRQLSEIEEEDKLLPTEDQSFNDLA
    HDVIHWIKEIKESLMVLNSSEGKMPLEERIQKIKEIILLKPEGDARIETI
    MKQAESSEAPLVQKTLTDISNQWDNTLHLASTYLSHQEKLLLEGEKYLQS
    KEDLRLMLIELKKKQEAGFALQHGLQEKKAQLKIYKKFLKKAQDLTSLLK
    ELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQDSVQNLDGHVRE
    HDSYQVCVTDLNTTLDNFSKEFVSFSDKPVDQIAVEEKLQKLQELENRLS
    LQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLASAK
    QEMECCLNSILKSKRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLE
    EDWEINKDSAVEMAMSKQLSLNAQESMKNTEDERKVNELQNQPLELDTML
    RNEQLEEIEKLYTQLEAKKAAIKPLEQTECLNKTETGALVLHNIGYSAQH
    LDNLLQALITLKKNKESQYCVLRDFQEYLAAVESSMKALLTDKESLKVGP
    LDSVTYLDKIKKFIASIEKEKDSLGNLKIKWENLSNHVTDMDKKLLESQI
    KQLEHGWEQVEQQIQKKYSQQVVEYDEFTTLMNKVQDTEISLQQQQQHLQ
    LRLKSPEERAGNQSMIALTTDLQATKHGFSVLKGQAELQMKRIWGEKEKK
    NLEDGINNLKKQWETLEPLHLEAENQIKKCDIRNKMKETILWAKNLLGEL
    NPSIPLLPDDILSQIRKCKVTHDGILARQQSVESLAEEVKDKVPSLTTYE
    GSDLNNTLEDLRNQYQMLVLKSTQRSQQLEFKLEERSNFFAIIRKFQLMV
    QESETLIIPRVETAATEAELKHHHVTLEASQKELQEIDSGISTHLQELTN
    IYEELNVFERLFLEDQLKNLKIRTNRIQRFIQNTCNEVEHKIKFCRQFHE
    KTSALQEEADSIQRNELLLNQEVNKGVKEEIYNLKDRLTAIKCCILQVLK
    LKKVFDYIGLNWDFSQLDQLQTQVFEKEKELEEKIKQLDTFEEEHGKYQA
    LLSKMRAIDLQIKKMTEVVLKAPDSSPESRRLNAQILSQRIEKAKCLCDE
    IIKKLNENKTFDDSFKEKEILQIKLNAEENDKLYKVLQNMVLELSPKELD
    EKNCQDKLETSLHVLNQIKSQLQQPLLINLEIKHIQNEKDNCEAFQEQVW
    AEMCSIKAVTAIEKQREENSSEASDVETKLREFEDLQMQLNTSIDLRTNV
    LNDAYENLTRYKEAVTRAVESITSLEAIIIPYRVDVGNPEESLEMPLRKQ
    EELESTVAHIQDLTEKLGMISSPEAKLQLQYTLQELVSKNSAMKEAFKAQ
    ETEAERYLENYKCYRKMEEDIYTNLSKMETVLGQSMSSLPLSYREALERL
    EQSKALVSNLISTKEELMKLRQILRLLRLRCTENDGICLLKIVSALWEKW
    LSLLEAAKEWEMWCEELKQEWKFVSEEIEREAIILDNLQEELPEISKTKE
    AATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIRSIQNVPESSGAVET
    VPAFQEITSMKERCNKLLQKVQKNKELVQTEIQERHSFTKEIIALKNFFQ
    QTTTSFQNMAFQDHPEKSEQFEELQSILKKGKLTFENIMEKLRIKYSEMY
    TIVPAEIESQVEECRKALEDIDEKISNEVLKSSPSYAMRRKIEEINNGLH
    NVEKMLQQKSKNIEKAQEIQKKMWDELDLWHSKLNELDSEVQDIVEQDPG
    QAQEWMDNLMIPFQQYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAW
    IENTSHLLANPADYDSLRTLSHHASTVQMALEDSEQKHNLLHSIFMDLED
    LSIIFETDELTQSIQELSNQVTALQQKIMESLPQIQRMADDVVAIESEVK
    SMEKRVSKIKTILLSKEIFDFSPEEHLKHGEVILENIRPMKKTIAEIVSY
    QVELRLPQTGMKPLPVFQRTNQLLQDIKLLENVTQEQNELLKVVIKQTNE
    WDEEIENLKQILNNYSAQFSLEHMSPDQADKLPQLQGEIERMEKQILSLN
    QRKEDLLVDLKATVLNLHQHLKQEQEGVERDRLPAVTSEEGGVAERDASE
    RKLNRRGSMSYLAAVEEEVEESSVKSDNGDEKAEPSPQSWSSLWKHDKDM
    EEDRASSSSGTIVQEAYGKISTSDNSMAQILTPDSLNTEQGPECSLRPNQ
    TEEGTTPPIEADTLDSSDAQGGLEPRVEKTRPEPTEVLHACKTQVAELEL
    WLQQANVAVEPETLNADMQQVLEQQLVGCQAMLTEIEHKVAFLLETCKDQ
    GLGDNGATQHEAEALSLKLKTVKCNLEKVQMMLQEKHSEDQHPTILKKSS
    EPEHQEALQPVNLSELESIVTERPQFSRQKDFQQQQVLELKPMEQKDFIK
    FIEFNAKKMWPQYCQHDNDTTQESSASNQASSPENDVPDSILSPQGQNGD
    KWQYLHHELSSKIKLPLPQLVEPQVSTNMGILPSVTMYNFRYPTTEELKT
    YTTQLEDLRQEASNLQTQENMTEEAYINLDKKLFELFLTLSQCLSSVEEM
    LEMPRLYREDGSGQQVHYETLALELKKLYLALSDKKGDLLKAMTWPGENT
    NLLLECFDNLQVCLEHTQAAAVCRSKSLKAGLDYNRSYQNEIKRLYHQLI
    KSKTSLQQSLNEISGQSVAEQLQKADAYTVELENAESRVAKLRDEGERLH
    LPYALLQEVYKLEDVLDSMWGMLRARYTELSSPFVTESQQDALLQGMVEL
    VKIGKEKLAHGHLKQTKSKVALQAQIENHKVFFQKLVADMLLIQAYSAKI
    LPSLLQNRETFWAEQVTEVKILEEKSRQCGMKLQSLLQKWEEFDENYASL
    EKDLEILISTLPSVSLVEETEERLVERISFYQQIKRNIGGKHARLYQTLN
    EGKQLVASVSCPELEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYN
    RDSDQLTKWLESSQHTLNYWKEQSLNVSQDLDTIRSNINNFFEFSKEVDE
    KSSLKTAVISIGNQLLHLKETDTATLRASLAQFEQKWTMLITQLPDIQEK
    LHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSASQVKHLLQK
    HKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQ
    WHRVHGMLNRKIQHLEQLLESITESENKIQILNNWLEAQEERLKTLQKPE
    SVISVQKLLLDCQDIENQLAIKSKALDELKQSYLTLESGAVPLLEDTASR
    IDELFQKRSSVLTQVNQLKTSMQSVLQEWKIYDQLYDEVNMMTIRFWYCM
    EHSKPVVLSLETLRCQVENLQSLQDEAESSEGSWEKLQEVIGKLKGLCPS
    VAEIIEEKCQNTHKRWTQVNQAIADQLQKAQSLLQLWKAYSNAHGEAAAR
    LKQQEAKFQQLANISMSGNNLAEILPPALQDIKELQHDVQKTKEAFLQNS
    SVLDRLPQPAESSTHMLLPGPLHSLQRAAYLEKMLLVKANEFEFVLSQFK
    DFGVRLESLKGLIMHEEENLDRLHQQEKENPDSFLNHVLALTAQSPDIEH
    LNEVSLKLPLSDVAVKTLQNMNRQWIRATATALERCSELQGIGLNEKFLY
    CCEKWIQLLEKIEEALKVDVANSLPELLEQQKTYKMLEAEVSINQTIADS
    YVTQSLQLLDTTEIENRPEFITEFSKLTDRWQNAVQGVRQRKGDVDGLVR
    QWQDFTTSVENLFRFLTDTSHLLSAVKGQERFSLYQTRSLIHELKNKEIH
    FQRRRTTCALTLEAGEKLLLTTDLKTKESVGRRISQLQDSWKDMEPQLAE
    MIKQFQSTVETWDQCEKKIKELKSRLQVLKAQSEDPLPELHEDLHNEKEL
    IKELEQSLASWTQNLKELQTMKADLTRHVLVEDVMVLKEQIEHLHRQWED
    LCLRVAIRKQEIEDRLNTWVVFNEKNKELCAWLVQMENKVLQTADISIEE
    MIEKLQKDCMEEINLFSENKLQLKQMGDQLIKASNKSRAAEIDDKLNKIN
    DRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVV
    YDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANE
    TECDSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFED
    WLKSAERTAACPNSSEVLYTSAKEELKRFEAFQRQIHERLTQLELINKQY
    RRLARENRTDTASRLKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEF
    EGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTNKI
    DQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSC
    TPGLEDEKEASENETDMEDPREIQTDSWRKRGESEEPSSPQSLCHLVAPG
    HERSGCETPVSVDSIPLEWDHTGDVGGSSSHEEDEEGPYYSALSGKSISD
    GHSWHVPDSPSCPEHHYKQMEGDRNVPPVPPASSTPYKPPYGKLLLPPGT
    DGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIK
    QNLQQLNSDISAITTWLKKTEAELEMLKMAKPPSDIQEIELRVKRLQEIL
    KAFDTYKALVVSVNVSSKEFLQTESPESTELQSRLRQLSLLWEAAQGAVD
    SWRGGLRQSLMQCQDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALL
    ECRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIE
    KKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPAPRAK
    QFRAVRTTEGEEETESRVPGSTRPQRSFLSRVVRAALPLQLLLLLLLLLA
    CLLPSSEEDYSCTQANNFARSFYPMLRYTNGPPPT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SYNE2
  • Full Name
  • Spectrin repeat containing nuclear envelope protein 2
  • Introduction
  • The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • SYNE2; NUA; EDMD5; KASH2; Nesp2; TROPH; NUANCE; SYNE-2; Nesprin-2; nesprin-2; KASH domain-containing protein 2; nesprin 2; nuclear envelope spectrin repeat protein 2; nucleus and actin connecting element protein; polytrophin; spectrin repeat containing, nuclear envelope 2; synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; Spectrin repeat containing nuclear envelope protein 2

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