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Magic™ Membrane Protein Human SYT8 (Synaptotagmin 8) Full Length (CAT#: MPC4660K) Made to Order

This product is a made-to-order Human SYT8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SYT8
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWA
    LIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHL
    VQPDVDGLESSPGDAQQWGCLQLSLEFDFGSQEIRVGLRQAADLRPGGTV
    DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQ
    LFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELC
    FSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK
    KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGAR
    ASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPH
    S

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SYT8
  • Full Name
  • Synaptotagmin 8
  • Introduction
  • This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • SYT8; synaptotagmin-8; synaptotagmin VIII; sytVIII; Synaptotagmin 8

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