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Magic™ Membrane Protein Human TGFBR3 (Transforming growth factor beta receptor 3) Expressed in NS0 for Antibody Discovery, Partial (21-781aa) (CAT#: MPX0709K)

This product is a 84 kDa Human TGFBR3 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TGFBR3
  • Protein Length
  • Partial (21-781aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 84 kDa
  • TMD
  • 1
  • Sequence
  • GPEPGALCELSPVSASHPVQALMESFTVLSGCASRGTTGL
    PQEVHVLNLALRQGPGQLQREVTLHLNPISSVHIHHKSVVFLLNSPHPLVWHLKTERLAT
    GVSRLFLVSEGSVVQFSSANFSLTAETEERNFPHGNEHLLNWARKEYGAVTSFTELKIAR
    NIYIKVGEDQVFPPKCNIGKNFLSLNYLAEYLQPKAAEGCVMSSQPQNEEVHIIELITPN
    SNPYSAFQVDITIDIRPSQEDLEVVKNLILILKCKKSVNWVIKSFDVKGSLKIIAPNSIG
    FGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVAIVFHLRLENNEEM
    GDEEVHTIPPELRILLDPGALPALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLP
    RPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQASGYSGMDVTL
    LDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYED
    LESGDNGFPGDMDEGDASLFTRPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDL
    FLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPK
    DESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPK
    CVPPDEACTSLDASIIWAMMQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGL
    D

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • TGFBR3
  • Full Name
  • Transforming growth factor beta receptor 3
  • Introduction
  • This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
  • Alternative Names
  • TGFBR3; BGCAN; betaglycan; transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGF-beta receptor type III; TGFR-3; betaglycan proteoglycan; transforming growth factor beta receptor III; Transforming growth factor beta receptor 3

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