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Magic™ Membrane Protein Human TMPRSS3 (Transmembrane serine protease 3) Full Length (CAT#: MPC1201K) Made to Order

Datasheet
This product is a 49.4 kDa Human TMPRSS3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TMPRSS3
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • Molecular Weight
  • 49.4 kDa
  • TMD
  • 1
  • Sequence
  • MGENDPPAVEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFP
    IIVIGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELIARCDGVSDCKD
    GEDEYRCVRVGGQNAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSY
    VSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVV
    TLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPL
    WIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKR
    LGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGA
    GDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGD
    SGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMER
    DLKT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TMPRSS3
  • Full Name
  • Transmembrane serine protease 3
  • Introduction
  • This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
  • Alternative Names
  • TMPRSS3; DFNB8; DFNB10; ECHOS1; TADG12; transmembrane protease serine 3; serine protease TADG-12; transmembrane protease, serine 3; tumor-associated differentially-expressed gene 12 protein; Transmembrane serine protease 3

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