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Magic™ Membrane Protein Human TMTC2 (Transmembrane O-mannosyltransferase targeting cadherins 2) Full Length (CAT#: MPC1377K) Made to Order

This product is a 94.1 kDa Human TMTC2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TMTC2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 94.1 kDa
  • TMD
  • 10
  • Sequence
  • MIAELVSSALGLALYLNTLSADFCYDDSRAIKTNQDLLPETPWTHIFYND
    FWGTLLTHSGSHKSYRPLCTLSFRLNHAIGGLNPWSYHLVNVLLHAAVTG
    LFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRADVGASLFFLL
    SLLCYIKHCSTRGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYD
    VFVFHRLKIKQILPTIYKRKNLSLFLSISLLIFWGSSLLGARLYWMGNKP
    PSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVP
    LLKTVCDWRNLHTVAFYTGLLLLAYYGLKSPSVDRECNGKTVTNGKQNAN
    GHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSL
    LIIPFVPATNLFFYVGFVIAERVLYIPSMGFCLLITVGARALYVKVQKRF
    LKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLG
    NVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY
    KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHA
    HKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMG
    EAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLF
    LKAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFN
    AAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEA
    NYLRALQLKPDDVITQSNLRKLWNIMEKQGLKTSKT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TMTC2
  • Full Name
  • Transmembrane O-mannosyltransferase targeting cadherins 2
  • Introduction
  • The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • TMTC2; IBDBP1; protein O-mannosyl-transferase TMTC2; transmembrane and TPR repeat-containing protein 2; transmembrane and tetratricopeptide repeat containing 2; Transmembrane O-mannosyltransferase targeting cadherins 2

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