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Magic™ Membrane Protein Human TOR1AIP2 (Torsin 1A interacting protein 2) Full Length (CAT#: MPC4116K) Made to Order

This product is a made-to-order Human TOR1AIP2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TOR1AIP2
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MADSGLREPQEDSQKDLENDPSVNSQAQETTIIASNAEEAEILHSACGLS
    KDHQEVETEGPESADTGDKSESPDEANVGKHPKDKTEDENKQSFLDGGKG
    HHLPSENLGKEPLDPDPSHSPSDKVGRADAHLGSSSVALPKEASDGTGAS
    QEPPTTDSQEAQSPGHSSAGQEGEDTLRRRLLAPEAGSHPQQTQKLEEIK
    ENAQDTMRQINKKGFWSYGPVILVVLVVAVVASSVNSYYSSPAQQVPKNP
    ALEAFLAQFSQLEDKFPGQSSFLWQRGRKFLQKHLNASNPTEPATIIFTA
    AREGRETLKCLSHHVADAYTSSQKVSPIQIDGAGRTWQDSDTVKLLVDLE
    LSYGFENGQKAAVVHHFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLL
    EEETLEASVGPRETEEKVRDLLWAKFTNSDTPTSFNHMDSDKLSGLWSRI
    SHLVLPVQPVSSIEEQGCLF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • TOR1AIP2
  • Full Name
  • Torsin 1A interacting protein 2
  • Introduction
  • One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined.
  • Alternative Names
  • TOR1AIP2; NET9; LULL1; IFRG15; torsin-1A-interacting protein 2; interferon alpha responsive protein; 15 kDa interferon-responsive protein; interferon responsive gene 15; lumenal domain like LAP1; torsin A interacting protein 2; Torsin 1A interacting protein 2

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