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Magic™ Membrane Protein Human TPO (Thyroid peroxidase) Expressed in Yeast with 6xHis tag at the N-terminus for Antibody Discovery, Partial (19-161aa) (CAT#: MPX4359K)

Datasheet
This product is a 17.9kDa Human TPO membrane protein expressed in Yeast. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TPO
  • Protein Length
  • Partial (19-161aa)
  • Protein Class
  • Oxidoreductase
  • Molecular Weight
  • 17.9kDa
  • TMD
  • 1
  • Sequence
  • FFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNR

Product Description

  • Expression Systems
  • Yeast
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • TPO
  • Full Name
  • Thyroid peroxidase
  • Introduction
  • This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
  • Alternative Names
  • TPO; MSA; TPX; TDH2A; thyroid microsomal antigen; thyroperoxidase; Thyroid peroxidase

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