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Magic™ Membrane Protein Human TREM2 (Triggering receptor expressed on myeloid cells 2) Expressed in NS0 for Antibody Discovery, Partial (19-174aa) (CAT#: MPX0193K)

Datasheet
This product is a 18 kDa Human TREM2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TREM2
  • Protein Length
  • Partial (19-174aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 18 kDa
  • TMD
  • 1
  • Sequence
  • HNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAW
    CRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNL
    QPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESF
    EDAHVEHSISRSLLEGEIPFPPTS

Product Description

  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in water.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in HEPES and NaCl.

Target

  • Target Protein
  • TREM2
  • Full Name
  • Triggering receptor expressed on myeloid cells 2
  • Introduction
  • This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • TREM2; PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; Triggering receptor expressed on myeloid cells 2

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