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This product is recombinant Human TRPM5 membrane protein. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.
Product Specifications
Host Species
Human
Target Protein
TRPM5
Protein Length
Full Length
Protein Class
Ion channel; Transport
TMD
6
Product Description
Tag
His tag
Target
Target Protein
TRPM5
Full Name
Transient receptor potential cation channel subfamily M member 5
Introduction
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
Alternative Names
MTR1; LTRPC5; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; long transient receptor potential channel 5