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Magic™ Membrane Protein Human VMP1 (Vacuole membrane protein 1) Full Length (CAT#: MPC2273K) Made to Order

This product is a 46.2 kDa Human VMP1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • VMP1
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 46.2 kDa
  • TMD
  • 7
  • Sequence
  • MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQP
    LITLQYFSLEILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQ
    QYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAY
    ECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAI
    GELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQK
    LVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIK
    MHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLH
    HKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLN
    SEEKTK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII and Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • VMP1
  • Full Name
  • Vacuole membrane protein 1
  • Introduction
  • This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy.
  • Alternative Names
  • VMP1; EPG3; TANGO5; TMEM49; ectopic P-granules autophagy protein 3 homolog; transmembrane protein 49; transport and golgi organization 5 homolog; Vacuole membrane protein 1

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