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Magic™ Membrane Protein Mouse Ctla4 (Cytotoxic T-lymphocyte-associated protein 4, 37-161aa) for Antibody Discovery (CAT#: MP1495J)

Datasheet
This product is a 14.6 kDa Mouse Ctla4 membrane protein expressed in Mammalian cell. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • Ctla4
  • Protein Length
  • Partial (37-161aa)
  • Protein Class
  • Immune Checkpoints
  • Molecular Weight
  • 14.6 kDa
  • TMD
  • 1
  • Sequence
  • AIQVTQPSVVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPFCSGTFNESRVNLTIQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTQIYVIDPEPCPDSD

Product Description

  • Activity
  • Validated by ELISA
  • Expression Systems
  • Mammalian cell
  • Tag
  • C-6xHis
  • Reconstitution
  • Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).
  • Endotoxin
  • <1.0 EU/μg
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • 0.2 μm filtered 1xPBS, pH 7.4

Target

  • Target Protein
  • Ctla4
  • Full Name
  • Cytotoxic T-lymphocyte-associated protein 4
  • Introduction
  • Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
  • Alternative Names
  • Ctla4; Cd152; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD antigen CD152; Ly-5; Ly-56; Ctla-4

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