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Magic™ Membrane Protein Rat Myc (MYC proto-oncogene, bHLH transcription factor) for Antibody Discovery (CAT#: MP1523J)

Datasheet
This product is Rat Myc membrane protein expressed in Yeast, E.coli, In Vivo Biotinylation, Baculovirus, or Mammalian cell. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Rat
  • Target Protein
  • Myc
  • Protein Length
  • Full length
  • Protein Class
  • Drug Target
  • Sequence
  • MPLNVSFANR NYDLDYDSVQ PYFICDEEEN FYHQQQQSEL QPPAPSEDIW KKFELLPTPP LSPSRRSGLC SPSYVAVATS FSPREDDDGG GGNFSTADQL EMMTELLGGD MVNQSFICDP DDETFIKNII IQDCMWSGFS AAAKLVSEKL ASYQAARKDS TSLSPARGHS VCSTSSLYLQ DLTAAASECI DPSVVFPYPL NDSSSPKSCT SSDSTAFSSS SDSLLSSESS PRATPEPLVL HEETPPTTSS DSEEEQDDEE EIDVVSVEKR QPPAKRSESG SSPSRGHSKP PHSPLVLKRC HVSTHQHNYA APPSTRKDYP AAKRAKLDSG RVLKQISNNR KCSSPRSSDT EENDKRRTHN VLERQRRNEL KRSFFALRDQ IPELENNEKA PKVVILKKAT AYILSVQADE HKLISEKDLL RKRREQLKHK LEQLRNSGA

Product Description

  • Expression Systems
  • Yeast
    E.coli
    In Vivo Biotinylation in E.coli
    Baculovirus
    Mammalian cell
  • Tag
  • N-His or Tag-Free
  • Reconstitution
  • Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).
  • Purity
  • >85% as determined by SDS-PAGE
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • Myc
  • Full Name
  • MYC proto-oncogene, bHLH transcription factor
  • Introduction
  • Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release.
  • Alternative Names
  • Myc; Myc proto-oncogene protein; Proto-oncogene c-Myc; Transcription factor p64; mMyc; c-myc; RNCMYC; Avian myelocytomatosis viral (v-myc) oncogene homolog; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog

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