Magic™ Membrane Protein SARS2 N Mutation (R203K, G204R) (Nucleocapsid phosphoprotein) Expressed in E.coli for Antibody Discovery, Partial (2-419aa) (CAT#: MPX0352K)

Datasheet

This product is a 46.5 kDa SARS2 N Mutation (R203K, G204R) membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
SARS2

Target Protein
N Mutation (R203K, G204R)

Protein Length
Partial (2-419aa)

Protein Class
Host-virus interaction

Molecular Weight
46.5 kDa

Sequence
SDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTA
SWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGK
MKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRN
PANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPG
SSKRTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKS
AAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKH
WPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTGAIKLDDKDPNFKDQV
ILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADL
DDFSKQLQQSMSSADSTQA

Product Description

Expression Systems
E.coli

Purity
> 85 % as determined by SDS-PAGE.

Buffer
Lyophilized from sterile 50 mM PB, 500 mM NaCl, pH 7.0.

Target

Target Protein
N Mutation (R203K, G204R)

Full Name
Nucleocapsid phosphoprotein

Introduction
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The nucleocapsid phosphoprotein is a structural protein that binds to, protects the viral RNA genome and is involved in packaging the RNA into virus particles. The N protein has been suggested as an antiviral drug target.

Alternative Names
N Mutation (R203K, G204R); ORF9; structural protein; Nucleocapsid phosphoprotein

Gene ID
43740575

UniProt ID
P0DTC9

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