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Magic™ Membrane Protein SARS2 orf3a (ORF3a protein) Expressed in cell-free expression system, Full Length (CAT#: MPX0372K)

This product is a 31.01 kDa SARS2 orf3a membrane protein expressed in cell-free expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • SARS2
  • Target Protein
  • orf3a
  • Protein Length
  • Full length
  • Protein Class
  • Host-virus interaction
  • Molecular Weight
  • 31.01 kDa
  • Sequence
  • MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGV
    ALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAG
    LEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWH
    TNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDC
    VVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTID
    GSSGVVNPVMEPIYDEPTTTTSVPL

Product Description

  • Expression Systems
  • Cell-free expression system

Target

  • Target Protein
  • orf3a
  • Full Name
  • ORF3a protein
  • Introduction
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF3a encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF3a protein is thought to be a protein with ion channel activity (viroporin) that activates the NLRP3 inflammasome. ORF3a may also play a role in virus replication and pathogenesis.
  • Alternative Names
  • orf3a; Accessory protein 3a; Protein 3a; Protein U274; Protein X1; ORF3a protein

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