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Magic™ Membrane Protein SARS2 S Mutation (G142S, E180V, Q677H, D614G) Protein (Surface glycoprotein) Reporter Virus Particles (CAT#: MPX2014K)

This product is a SARS2 S Mutation (G142S, E180V, Q677H, D614G) protein Reporter Virus Particles. Reporter Virus Particles (RVPs) are replication-incompetent pseudotyped virus particles. RVPs display antigenically correct virus protein on a heterologous virus core and carry a modified genome that expresses a convenient optical reporter gene (GFP or luciferase). The product is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • SARS2
  • Target Protein
  • S Mutation (G142S, E180V, Q677H, D614G)
  • Protein Class
  • Host-virus interaction
  • TMD
  • 1
  • Sequence
  • MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHS
    TQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNI
    IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLSVYYHKNNK
    SWMESEFRVYSSANNCTFEYVSQPFLMDLVGKQGNFKNLREFVFKNIDGY
    FKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLT
    PGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETK
    CTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV
    YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSF
    VIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYN
    YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPT
    NGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTG
    VLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITP
    GTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCL
    IGAEHVNNSYECDIPIGAGICASYQTHTNSPRRARSVASQSIIAYTMSLG
    AENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS
    NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGF
    NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLI
    CAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAM
    QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQD
    VVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGR
    LQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLM
    SFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGT
    HWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKE
    ELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL
    QELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSC
    GSCCKFDEDDSEPVLKGVKLHYT

Product Description

  • Protein Format
  • Reporter Virus Particles

Target

  • Target Protein
  • S Mutation (G142S, E180V, Q677H, D614G)
  • Full Name
  • Surface glycoprotein
  • Introduction
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
  • Alternative Names
  • S Mutation (G142S, E180V, Q677H, D614G); structural protein; spike protein; Surface glycoprotein; SARS2; SARS-CoV-2; Reporter Virus Particles; RVPs

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